{"id":6559,"date":"2026-10-13T23:18:15","date_gmt":"2026-10-13T16:18:15","guid":{"rendered":"https:\/\/dykhoa.com\/blog\/?post_type=thuat_ngu&#038;p=6559"},"modified":"2026-10-13T23:18:15","modified_gmt":"2026-10-13T16:18:15","slug":"tinh-bat-doi-chirality","status":"publish","type":"thuat_ngu","link":"https:\/\/dykhoa.com\/blog\/thuat-ngu\/tinh-bat-doi-chirality\/","title":{"rendered":"T\u00ednh b\u1ea5t \u0111\u1ed1i (chirality) l\u00e0 g\u00ec?"},"content":{"rendered":"<p>\u0110\u1eb7t b\u00e0n tay tr\u00e1i l\u00ean b\u00e0n tay ph\u1ea3i, b\u1ea1n s\u1ebd th\u1ea5y ch\u00fang l\u00e0 \u1ea3nh g\u01b0\u01a1ng c\u1ee7a nhau nh\u01b0ng kh\u00f4ng ch\u1ed3ng kh\u00edt \u0111\u01b0\u1ee3c. Nhi\u1ec1u ph\u00e2n t\u1eed c\u0169ng v\u1eady. IUPAC (2025) \u0111\u1ecbnh ngh\u0129a t\u00ednh b\u1ea5t \u0111\u1ed1i l\u00e0 t\u00ednh ch\u1ea5t h\u00ecnh h\u1ecdc c\u1ee7a m\u1ed9t v\u1eadt c\u1ee9ng, ho\u1eb7c m\u1ed9t c\u00e1ch s\u1eafp x\u1ebfp nguy\u00ean t\u1eed trong kh\u00f4ng gian, kh\u00f4ng th\u1ec3 ch\u1ed3ng kh\u00edt l\u00ean \u1ea3nh g\u01b0\u01a1ng c\u1ee7a n\u00f3; v\u1eadt ch\u1ed3ng kh\u00edt \u0111\u01b0\u1ee3c l\u00ean \u1ea3nh g\u01b0\u01a1ng th\u00ec g\u1ecdi l\u00e0 kh\u00f4ng b\u1ea5t \u0111\u1ed1i.<\/p>\n<h2>V\u00ec sao t\u00ednh b\u1ea5t \u0111\u1ed1i quan tr\u1ecdng v\u1edbi thu\u1ed1c?<\/h2>\n<p>Hai d\u1ea1ng \u1ea3nh g\u01b0\u01a1ng c\u1ee7a c\u00f9ng m\u1ed9t ph\u00e2n t\u1eed c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c c\u01a1 th\u1ec3 ph\u00e2n bi\u1ec7t r\u1ea5t r\u00f5, v\u1edbi t\u00e1c d\u1ee5ng d\u01b0\u1ee3c l\u00fd ho\u1eb7c \u0111\u1ed9c t\u00ednh kh\u00e1c nhau v\u1ec1 l\u01b0\u1ee3ng hay v\u1ec1 ch\u1ea5t; \u0111\u1ed9c t\u00ednh c\u00f3 khi g\u1eafn v\u1edbi d\u1ea1ng kh\u00f4ng ph\u1ea3i l\u00e0 d\u1ea1ng c\u00f3 t\u00e1c d\u1ee5ng ch\u1eefa b\u1ec7nh (FDA, 1992). V\u00ec th\u1ebf, h\u01b0\u1edbng d\u1eabn n\u0103m 1992 c\u1ee7a FDA khuy\u1ebfn c\u00e1o r\u1eb1ng th\u00e0nh ph\u1ea7n \u0111\u1ed3ng ph\u00e2n l\u1eadp th\u1ec3 c\u1ee7a m\u1ed9t thu\u1ed1c c\u00f3 trung t\u00e2m b\u1ea5t \u0111\u1ed1i c\u1ea7n \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh r\u00f5.<\/p>\n<ul>\n<li><strong>V\u00ed d\u1ee5 thalidomide:<\/strong> trong giai \u0111o\u1ea1n 1957 \u0111\u1ebfn 1962, thu\u1ed1c n\u00e0y g\u00e2y d\u1ecb t\u1eadt b\u1ea9m sinh n\u1eb7ng \u1edf h\u01a1n 10.000 tr\u1ebb. D\u1ea1ng S \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 g\u00e2y qu\u00e1i thai, nh\u01b0ng hai d\u1ea1ng c\u00f3 th\u1ec3 chuy\u1ec3n \u0111\u1ed5i qua l\u1ea1i nhanh trong d\u1ecbch c\u01a1 th\u1ec3, n\u00ean r\u1ea5t kh\u00f3 t\u1ea1o ra m\u1ed9t d\u1ea1ng b\u1ec1n m\u00e0 kh\u00f4ng g\u00e2y qu\u00e1i thai (Vargesson, 2015).<\/li>\n<\/ul>\n<h2>Gi\u1ea3i Nobel H\u00f3a h\u1ecdc 2026 li\u00ean quan g\u00ec \u0111\u1ebfn t\u00ednh b\u1ea5t \u0111\u1ed1i?<\/h2>\n<p>M\u1ed9t s\u1ed1 ph\u00e2n t\u1eed c\u1ee7a s\u1ef1 s\u1ed1ng, nh\u01b0 axit amin, c\u00f3 hai d\u1ea1ng \u1ea3nh g\u01b0\u01a1ng, nh\u01b0ng c\u01a1 th\u1ec3 sinh v\u1eadt ch\u1ec9 ch\u1ee9a m\u1ed9t trong hai d\u1ea1ng. Gi\u1ea3i Nobel H\u00f3a h\u1ecdc 2026 \u0111\u01b0\u1ee3c trao cho Henri B. Kagan (Universit\u00e9 Paris-Sud, Ph\u00e1p) v\u00e0 Kenso Soai (\u0110\u1ea1i h\u1ecdc Khoa h\u1ecdc Tokyo, Nh\u1eadt B\u1ea3n) \u201cv\u00ec kh\u00e1m ph\u00e1 c\u00e1c hi\u1ec7u \u1ee9ng phi tuy\u1ebfn v\u00e0 hi\u1ec7n t\u01b0\u1ee3ng t\u1ef1 x\u00fac t\u00e1c trong t\u1ed5ng h\u1ee3p h\u1eefu c\u01a1 b\u1ea5t \u0111\u1ed1i x\u1ee9ng\u201d (Royal Swedish Academy of Sciences, 2026). B\u00e0i <a href=\"https:\/\/dykhoa.com\/blog\/nobel-hoa-hoc-2026-tong-hop-bat-doi-xung\/\">Nobel H\u00f3a h\u1ecdc 2026: ph\u00e2n t\u1eed tay tr\u00e1i, tay ph\u1ea3i<\/a> gi\u1ea3i th\u00edch k\u1ef9 h\u01a1n.<\/p>\n<h2>C\u00e2u h\u1ecfi th\u01b0\u1eddng g\u1eb7p<\/h2>\n<h3>Ph\u00e2n t\u1eed b\u1ea5t \u0111\u1ed1i c\u00f3 ph\u1ea3i l\u00e0 ph\u00e2n t\u1eed \u201cb\u1ea5t \u0111\u1ed1i x\u1ee9ng\u201d ho\u00e0n to\u00e0n?<\/h3>\n<p>Kh\u00f4ng h\u1eb3n. Theo IUPAC (2025), \u0111i\u1ec1u quy\u1ebft \u0111\u1ecbnh l\u00e0 v\u1eadt kh\u00f4ng c\u00f3 c\u00e1c y\u1ebfu t\u1ed1 \u0111\u1ed1i x\u1ee9ng lo\u1ea1i hai, nh\u01b0 m\u1eb7t ph\u1eb3ng g\u01b0\u01a1ng, t\u00e2m \u0111\u1ed1i x\u1ee9ng hay tr\u1ee5c quay ph\u1ea3n x\u1ea1.<\/p>\n<h3>C\u00f3 n\u00ean lo khi th\u1ea5y thu\u1ed1c ghi m\u1ed9t d\u1ea1ng \u0111\u1ed3ng ph\u00e2n c\u1ee5 th\u1ec3?<\/h3>\n<p>Th\u01b0\u1eddng th\u00ec kh\u00f4ng c\u1ea7n lo. H\u01b0\u1edbng d\u1eabn c\u1ee7a FDA (1992) \u0111\u1ec1 ngh\u1ecb t\u00ean thu\u1ed1c k\u00e8m k\u00fd hi\u1ec7u l\u1eadp th\u1ec3 ph\u00f9 h\u1ee3p \u0111\u1ec3 m\u00f4 t\u1ea3 ch\u00ednh x\u00e1c ho\u1ea1t ch\u1ea5t. M\u1ecdi th\u1eafc m\u1eafc v\u1ec1 thu\u1ed1c \u0111ang d\u00f9ng n\u00ean h\u1ecfi b\u00e1c s\u0129 ho\u1eb7c d\u01b0\u1ee3c s\u0129. Xem th\u00eam b\u00e0i <a href=\"https:\/\/dykhoa.com\/blog\/doc-tin-giai-nobel-the-nao-cho-dung\/\">\u0111\u1ecdc tin gi\u1ea3i Nobel th\u1ebf n\u00e0o cho \u0111\u00fang<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>T\u00ednh b\u1ea5t \u0111\u1ed1i (chirality) l\u00e0 khi ph\u00e2n t\u1eed kh\u00f4ng ch\u1ed3ng kh\u00edt l\u00ean \u1ea3nh g\u01b0\u01a1ng c\u1ee7a n\u00f3, nh\u01b0 hai b\u00e0n tay. V\u00ec sao \u0111i\u1ec1u n\u00e0y quan tr\u1ecdng v\u1edbi thu\u1ed1c?<\/p>\n","protected":false},"author":1,"featured_media":0,"template":"","nhom_thuat_ngu":[472],"class_list":["post-6559","thuat_ngu","type-thuat_ngu","status-publish","hentry","nhom_thuat_ngu-truyen-thong-khoa-hoc"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>T\u00ednh b\u1ea5t \u0111\u1ed1i (chirality) l\u00e0 g\u00ec? - Dy Khoa Blog<\/title>\n<meta name=\"description\" content=\"T\u00ednh b\u1ea5t \u0111\u1ed1i (chirality) l\u00e0 khi ph\u00e2n t\u1eed kh\u00f4ng ch\u1ed3ng kh\u00edt l\u00ean \u1ea3nh g\u01b0\u01a1ng c\u1ee7a n\u00f3, nh\u01b0 hai b\u00e0n tay. 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