{"id":5029,"date":"2026-10-12T08:00:00","date_gmt":"2026-10-12T01:00:00","guid":{"rendered":"https:\/\/dykhoa.com\/blog\/?post_type=thuat_ngu&#038;p=5028"},"modified":"2026-10-14T07:49:19","modified_gmt":"2026-10-14T00:49:19","slug":"phan-tich-tong-hop-gop-mang-luoi-network-meta-analysis","status":"publish","type":"thuat_ngu","link":"https:\/\/dykhoa.com\/blog\/thuat-ngu\/phan-tich-tong-hop-gop-mang-luoi-network-meta-analysis\/","title":{"rendered":"Ph\u00e2n t\u00edch t\u1ed5ng h\u1ee3p g\u1ed9p m\u1ea1ng l\u01b0\u1edbi (network meta-analysis) l\u00e0 g\u00ec?"},"content":{"rendered":"<h2>Ph\u00e2n t\u00edch t\u1ed5ng h\u1ee3p g\u1ed9p m\u1ea1ng l\u01b0\u1edbi l\u00e0 g\u00ec?<\/h2>\n<p>Ph\u00e2n t\u00edch t\u1ed5ng h\u1ee3p g\u1ed9p m\u1ea1ng l\u01b0\u1edbi (network meta-analysis, NMA), c\u00f2n g\u1ecdi l\u00e0 so s\u00e1nh \u0111i\u1ec1u tr\u1ecb h\u1ed7n h\u1ee3p (mixed treatment comparison) hay ph\u00e2n t\u00edch g\u1ed9p \u0111a \u0111i\u1ec1u tr\u1ecb (multiple-treatments meta-analysis), so s\u00e1nh \u0111\u1ed3ng th\u1eddi t\u1eeb ba can thi\u1ec7p tr\u1edf l\u00ean trong m\u1ed9t ph\u00e2n t\u00edch b\u1eb1ng c\u00e1ch k\u1ebft h\u1ee3p b\u1eb1ng ch\u1ee9ng tr\u1ef1c ti\u1ebfp v\u00e0 gi\u00e1n ti\u1ebfp (Chaimani v\u00e0 cs., 2024). Nh\u1edd \u0111\u00f3, NMA c\u00f3 th\u1ec3 \u01b0\u1edbc l\u01b0\u1ee3ng hi\u1ec7u qu\u1ea3 t\u01b0\u01a1ng \u0111\u1ed1i gi\u1eefa hai thu\u1ed1c A v\u00e0 B ngay c\u1ea3 khi ch\u01b0a c\u00f3 th\u1eed nghi\u1ec7m so s\u00e1nh tr\u1ef1c ti\u1ebfp (head-to-head trial), d\u1ef1a tr\u00ean c\u00e1c th\u1eed nghi\u1ec7m so s\u00e1nh A v\u1edbi C v\u00e0 B v\u1edbi C (Caldwell v\u00e0 cs., 2005).<\/p>\n<h2>NMA \u0111\u01b0\u1ee3c d\u00f9ng th\u1ebf n\u00e0o trong y h\u1ecdc d\u1ef1a tr\u00ean b\u1eb1ng ch\u1ee9ng?<\/h2>\n<p>M\u1ed9t v\u00ed d\u1ee5 n\u1ed5i b\u1eadt l\u00e0 NMA c\u1ee7a Cipriani v\u00e0 cs. (2018), t\u1ed5ng h\u1ee3p 522 th\u1eed nghi\u1ec7m m\u00f9 \u0111\u00f4i ng\u1eabu nhi\u00ean v\u1edbi 116.477 ng\u01b0\u1eddi tham gia \u0111\u1ec3 so s\u00e1nh 21 thu\u1ed1c ch\u1ed1ng tr\u1ea7m c\u1ea3m; t\u1ea5t c\u1ea3 c\u00e1c thu\u1ed1c \u0111\u1ec1u hi\u1ec7u qu\u1ea3 h\u01a1n gi\u1ea3 d\u01b0\u1ee3c \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh m\u1eafc r\u1ed1i lo\u1ea1n tr\u1ea7m c\u1ea3m ch\u1ee7 y\u1ebfu. NMA c\u0169ng cho ph\u00e9p x\u1ebfp h\u1ea1ng c\u00e1c can thi\u1ec7p, nh\u01b0ng Cochrane khuy\u1ebfn c\u00e1o kh\u00f4ng suy lu\u1eadn ch\u1ec9 d\u1ef1a tr\u00ean x\u00e1c su\u1ea5t \u0111\u01b0\u1ee3c x\u1ebfp h\u1ea1ng t\u1ed1t nh\u1ea5t m\u00e0 b\u1ecf qua \u0111\u1ed9 b\u1ea5t \u0111\u1ecbnh (Chaimani v\u00e0 cs., 2024).<\/p>\n<h2>Nh\u1eefng \u0111i\u1ec3m l\u01b0u \u00fd quan tr\u1ecdng<\/h2>\n<ul>\n<li><strong>Gi\u1ea3 \u0111\u1ecbnh b\u1eafc c\u1ea7u (transitivity):<\/strong> so s\u00e1nh gi\u00e1n ti\u1ebfp ch\u1ec9 h\u1ee3p l\u1ec7 khi c\u00e1c nh\u00f3m th\u1eed nghi\u1ec7m t\u01b0\u01a1ng \u0111\u1ed3ng v\u1ec1 c\u00e1c y\u1ebfu t\u1ed1 quan tr\u1ecdng, nh\u01b0 y\u1ebfu t\u1ed1 l\u00e0m thay \u0111\u1ed5i hi\u1ec7u qu\u1ea3, ngo\u00e0i can thi\u1ec7p \u0111\u01b0\u1ee3c so s\u00e1nh (Chaimani v\u00e0 cs., 2024).<\/li>\n<li><strong>B\u1ea5t nh\u1ea5t qu\u00e1n (incoherence):<\/strong> b\u1eb1ng ch\u1ee9ng tr\u1ef1c ti\u1ebfp v\u00e0 gi\u00e1n ti\u1ebfp c\u00f3 th\u1ec3 m\u00e2u thu\u1eabn; ki\u1ec3m \u0111\u1ecbnh b\u1ea5t nh\u1ea5t qu\u00e1n c\u00f3 \u0111\u1ed9 m\u1ea1nh th\u1ea5p, n\u00ean k\u1ebft qu\u1ea3 kh\u00f4ng c\u00f3 \u00fd ngh\u0129a th\u1ed1ng k\u00ea ch\u01b0a ch\u1ee9ng minh \u0111\u01b0\u1ee3c s\u1ef1 nh\u1ea5t qu\u00e1n (Chaimani v\u00e0 cs., 2024).<\/li>\n<li><strong>Kh\u00f4ng ng\u1eabu nhi\u00ean h\u00f3a gi\u1eefa c\u00e1c th\u1eed nghi\u1ec7m:<\/strong> so s\u00e1nh gi\u00e1n ti\u1ebfp c\u00f3 th\u1ec3 ch\u1ecbu sai l\u1ec7ch t\u01b0\u01a1ng t\u1ef1 nghi\u00ean c\u1ee9u quan s\u00e1t (Caldwell v\u00e0 cs., 2005).<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Ph\u00e2n t\u00edch t\u1ed5ng h\u1ee3p g\u1ed9p m\u1ea1ng l\u01b0\u1edbi (network meta-analysis) l\u00e0 g\u00ec? C\u00e1ch so s\u00e1nh nhi\u1ec1u can thi\u1ec7p c\u00f9ng l\u00fac, v\u00ed d\u1ee5 th\u1ef1c t\u1ebf v\u00e0 c\u00e1c gi\u1ea3 \u0111\u1ecbnh c\u1ea7n l\u01b0u \u00fd.<\/p>\n","protected":false},"author":1,"featured_media":0,"template":"","nhom_thuat_ngu":[476],"class_list":["post-5029","thuat_ngu","type-thuat_ngu","status-publish","hentry","nhom_thuat_ngu-nghien-cuu-bang-chung"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Ph\u00e2n t\u00edch t\u1ed5ng h\u1ee3p g\u1ed9p m\u1ea1ng l\u01b0\u1edbi (network meta-analysis) l\u00e0 g\u00ec? - Dy Khoa Blog<\/title>\n<meta name=\"description\" content=\"Ph\u00e2n t\u00edch t\u1ed5ng h\u1ee3p g\u1ed9p m\u1ea1ng l\u01b0\u1edbi (network meta-analysis) l\u00e0 g\u00ec? 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